Supplement with ingredients studied for combatting glycation

Anti-Glycation Formula is a state-of-the-art supplement based on the latest scientific findings on glycation. It contains, in particular, benfotiamine and pyridoxamine, vitamins that help maintain good cardiovascular and nervous system function, both of which are key targets of glycation and oxidative stress.

What is glycation?

Glycation is a spontaneous and irreversible chemical reaction which occurs between a sugar (particularly glucose) and a protein (whether a tissue or circulating protein, extracellular or intracellular). It is a completely normal process but is accelerated in certain pathological situations such as diabetes, chronic stress or atherosclerosis.

It leads to the formation of ‘glycated’ proteins (glycation end-products) (1-2) which cannot be destroyed or eliminated, and so accumulate in the body, disrupting cell, hormone and organ function, etc. Proteins that play a fundamental role as hormones (insulin) or growth factors lose their function when they become glycated. Accumulated glycated proteins activate inflammatory cells and promote oxidative reactions which are again damaging for the body.

The types of protein most affected include albumin, insulin, haemoglobin, immunoglobulin, lipoprotein, fibrinogen, and of course, collagen, elastin and DNA (deoxyribonucleic acid).

Glycation has a significant effect in accelerating the processes governing ageing, just like oxidation with which it is associated.

How can you fight glycation?

Skin ageing is the most obvious sign of the consequences of glycation: wrinkles, loss of elasticity and reduced healing ability. But the skin is just the visible manifestation of changes affecting the whole body – the muscles, blood vessels, eyes, brain and many other organs.
When there are too many non-functional proteins, the body becomes a target for degenerative diseases and ages prematurely. It’s therefore advisable to take a sensible, long-term approach to restricting this natural and irreversible process, by using glycation inhibitors, which are well-documented in the scientific literature, and by reducing your blood sugar levels naturally. Elevated blood glucose leads to an acceleration in glycation.